A table reporting signed human TF-target interactions for cancer application. The difference to "dorothea_hs" is that TGCA gene expression data was used instead of GTEx to infer the networks with ARACNE. This database covers in total 1344 TFs targeting 20,582 genes with 213,230 unique interactions. In addition, each TF is accompanied with an empirical confidence level that was derived from the number of supporting evidences for this TF/interaction. The range is from A (high quality) to E (low quality).
A table of human TF-target interactions:
TF identifier as HGNC symbols
Summary confidence score classifying regulons based on their quality
target identifier as HGNC symbols
mode of regulation indicating the effect of a TF on the target