Metabolism

CORNETO can be used to infer and contextualize metabolic networks. In this tutorial, we will show how to use CORNETO to infer a metabolic network from a gene expression dataset and a metabolic model. We will then show how to contextualize the inferred network with prior knowledge.

• Flux Balance Analysis (FBA)
  • What is FBA?
  • FBA with CORNETO
  • Using COBRApy
• Sparse FBA
  • Manual implementation of sparse FBA
  • Sparse FBA with min. flux
• Multi-condition sparse FBA
• Context-specific models (iMAT)
• Multi-condition iMAT