This signaling data are a subset of the footprint-based signaling activity estimates of transcription factors, kinases and phophatases used as an input in the case study of the COSMOS paper. The subset contains a random selection of signaling proteins present in the toy network.

data(toy_signaling_input)

Format

An object of class “data.frame” containing the normalised enrichment scores (NES) of 2 signaling proteins, which are named with their respective gene Entrez ID matching the toy network.

Source

Subset of: https://github.com/saezlab/COSMOS_MSB/blob/main/data/signaling_input_COSMOS.csv

References

Dugourd, A., Kuppe, C. and Sciacovelli, M. et. al. (2021) Molecular Systems Biology. 17, e9730.

Examples

toy_signaling_input = toy_signaling_input