MetaProViz (Metabolomics Processing, functional analysis and Visualization), a free open-source R-package that provides mechanistic hypotheses from metabolomics data by integrating prior knowledge from literature with metabolomics. MetaProViz offers an interactive framework consisting of five modules: Processing, differential analysis, prior knowledge access and refactoring, functional analysis and visualization of both intracellular and exometabolomics (consumption-release/core data).